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    Management of Skull-Base Meningiomas With Extracranial Extensions: Clinical Features, Radiological Findings, Surgical Strategies, and Long-Term Outcomes

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  • Optometry

    is this change in contact prescription normal? i haven’t received the new contacts yet

    Long term eye issue

    visual flashes?

    suggestion for sunglasses for people with high prescription

    Do you have visual snow (TV like static over the field of vision)

    slightly enlarged optic nerve

    High Myopia glasses

    90D or SuperField in community optometry?? (UK)

    Need to see eye specialist before the appointment date.

  • Research

    Management of Skull-Base Meningiomas With Extracranial Extensions: Clinical Features, Radiological Findings, Surgical Strategies, and Long-Term Outcomes

    Dynamic Evolution of the Glymphatic System at the Early Stages of Subarachnoid Hemorrhage

    Prominent Fatigue but No Motor Fatigability in Non-Hospitalized Patients With Post-COVID-Syndrome

    Efficacy and Safety of Vagus Nerve Stimulation on Upper Limb Motor Recovery After Stroke. A Systematic Review and Meta-Analysis

    Corrigendum: Editorial: Visual Snow: Old Problem, New Understanding

    An Improved Surgical Technique to Increase Neck Width of Elastase-Induced Aneurysm Model in Rabbits: A Prospective Study

    Quantifying the Cerebral Hemometabolic Response to Blood Transfusion in Pediatric Sickle Cell Disease With Diffuse Optical Spectroscopies

    Effects of the CarFreeMe Traumatic Injuries, a Community Mobility Group Intervention, to Increase Community Participation for People With Traumatic Injuries: A Randomized Controlled Trial With Crossover

    Systolic Blood Pressure Variability When Transitioning From Intravenous to Enteral Antihypertensive Agents in Patients With Hemorrhagic Strokes

  • Myopia

    Could I use both contact lenses AND glasses to get better vision?

    As at July 2022 — do these Single Vision lenses TRULY slow myopia, for kids?

    would you rather have myopia or losing one eyes but have 20/20 in the other?

    Has my eyes changed?

    I’m a -3.50 OD -3.25 OS. How concerned should I be about Retinal Detachment?

    Should I wear my glasses at school, my left is -1.00 and my right is -2.00

    I’m Old Greeeeeeeegg!

    What’s the symptoms of having too much astigmatism correction?

    endmyopia

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Secondary Prevention in Radiologically Isolated Syndromes and Prodromal Stages of Multiple Sclerosis

by Neuroptometry
March 14, 2022
in Research
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Following the extraordinary progress in the treatment of multiple sclerosis (MS), two major unmet needs remain: understanding the etiology of the disease and, hence, designing definitive cures (this perspective is neither at hand, nor it can be taken for granted that the etiologic targets will be readily treatable); the prevention of an overt and disabling disease, which seems to be a more realistic and pragmatic perspective, as the integration of genetic data with endophenotypes, MRI, and other biomarkers ameliorates our ability to identify early neuroinflammation. Radiologically isolated syndrome (RIS; diagnosed when the unanticipated MRI finding of brain spatial dissemination of focal white matter lesions highly suggestive of MS occurs in subjects without symptoms of MS, and with normal neurological examinations) and the recently focused “prodromal MS” are conditions at risk of conversion toward overt disease. Here, we explore the possibility of secondary prevention approaches in these early stages of neuroinflammation. RIS and prodromal MS are rare conditions, which suggest the importance of Study Groups and Disease Registry to implement informative clinical trials. We summarize ongoing preventive approaches in the early stages of the demyelinating process, especially in RIS conditions. Moreover, we highlight the importance of the biomarkers and the predictors of evolution to overt disease, which may be useful to select the individuals at risk of conversion to clinically isolated syndrome (CIS) and/or clinically definite MS. Finally, we illustrate the importance of the endophenotypes to test the frontline immunomodulatory approach for preventive strategies. Future investigations, especially in relatives of patients, based on MRI techniques and biological studies (better with integrated approaches) may provide opportunities to understand the MS early causal cascade and may help to identify a “therapeutic window” to potentially reverse early disease processes.

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FEATURED POST

Management of Skull-Base Meningiomas With Extracranial Extensions: Clinical Features, Radiological Findings, Surgical Strategies, and Long-Term Outcomes

July 3, 2022

Dynamic Evolution of the Glymphatic System at the Early Stages of Subarachnoid Hemorrhage

July 3, 2022

Prominent Fatigue but No Motor Fatigability in Non-Hospitalized Patients With Post-COVID-Syndrome

July 3, 2022

Efficacy and Safety of Vagus Nerve Stimulation on Upper Limb Motor Recovery After Stroke. A Systematic Review and Meta-Analysis

July 3, 2022

EDITOR PICK'S

Management of Skull-Base Meningiomas With Extracranial Extensions: Clinical Features, Radiological Findings, Surgical Strategies, and Long-Term Outcomes

July 3, 2022

Dynamic Evolution of the Glymphatic System at the Early Stages of Subarachnoid Hemorrhage

July 3, 2022

Prominent Fatigue but No Motor Fatigability in Non-Hospitalized Patients With Post-COVID-Syndrome

July 3, 2022

Efficacy and Safety of Vagus Nerve Stimulation on Upper Limb Motor Recovery After Stroke. A Systematic Review and Meta-Analysis

July 3, 2022

Corrigendum: Editorial: Visual Snow: Old Problem, New Understanding

July 3, 2022

is this change in contact prescription normal? i haven’t received the new contacts yet

July 3, 2022

Long term eye issue

July 3, 2022
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Management of Skull-Base Meningiomas With Extracranial Extensions: Clinical Features, Radiological Findings, Surgical Strategies, and Long-Term Outcomes

July 3, 2022

Dynamic Evolution of the Glymphatic System at the Early Stages of Subarachnoid Hemorrhage

July 3, 2022

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